Opioid-related harms and care impacts of conventional and AI-based prescription management strategies: insights from leveraging agent-based modeling and machine learning

IntroductionLike its counterpart to the south, Canada ranks among the top five countries with the highest rates of opioid prescriptions.With many suffering from opioid use disorder first having encountered opioids via prescription routes, practitioners and health systems have an enduring need to identify and effectively respond to the problematic u

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In-silico modeling of the mitotic spindle assembly checkpoint.

The Mitotic Spindle Assembly Checkpoint ((M)SAC) is an evolutionary conserved mechanism that ensures the correct segregation of chromosomes by restraining cell cycle progression from entering anaphase until all chromosomes have made proper bipolar attachments to the mitotic spindle.Its malfunction can lead to cancer.We have Bridal Party Dresses con

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Antifactors of regular bipartite graphs

Let $G=(X,Y;E)$ be a bipartite graph, where $X$ and $Y$ are color classes and $E$ Breath Spray is the set of edges of $G$.Lov'asz and Plummer cite{LoPl86} asked whether one can decide in polynomial time that a given bipartite graph $G=(X,Y; E)$ admits a 1-anti-factor, that is subset $F$ of $E$ such that $d_F(v)=1$ for all $vin X$ and $d_F(v) eq 1$

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Introducing untb, an R Package For Simulating Ecological Drift Under the Unified Neutral Theory of Biodiversity

The distribution of abundance amongst species with similar ways of life is a classical problem in ecology.The unified neutral theory of biodiversity, due to Hubbell, states that observed population dynamics may be explained on the assumption of per capita equivalence amongst individuals.One can thus dispense with differences between species, and di

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